WiscOnline was developed by Wisconsin Technical College System to address basic digital literacy skills, and allows people to sign in and keep track of their own progress. Free to use.
Northstar Digital Literacy Project has basic computer digital literacy standards and self-guided modules and assessments in six main areas: Basic Computer Use, Internet, Windows, Mac, Email and Word Processing.
Goodwill Industries has a comprehensive, free online resource for learning software, typing and mouse skills
Palm Beach County Library has some excellent and fun exercises to practice using the mouse
Everyoneon is a national initiative to help people who need training and information on using the Internet. Links to free training classes, online tutorials and more.